Testing narmafotinib in combination with FOLFIRINOX for the treatment of metastatic pancreatic cancer.
Amplia is developing a type of drug called a FAK inhibitor which we hope will make cancers more vulnerable and responsive to currently used treatments.
Our FAK inhibitor, narmafotinib, aims to break down the fibrotic tissue shield that forms around pancreatic cancer cells to allow the chemotherapy to be more effective.
Amplia has successfully undertaken vital research and development milestones to get to this stage. Our clinical trial sites in the US are preparing to recruit and in Australia are active and we are recruiting participants for our Amplicity trial as we test if narmafotinib, used in combination with a standard of care chemotherapy drug regimen called FOLFIRINOX, is effective in treating metastatic pancreatic cancer.
The Amplicity Clinical Trial (AMP945-PC-201) has strict entry criteria. Please note, Amplia is not recruiting patients directly and all enquiries for involvement must be made via our clinical trial sites.
The trial is currently recruiting
Clinical trial sites are located in Australia and the United States.
The Amplicity trial will test if narmafotinib helps people with pancreatic cancer have a better response to a commonly used chemotherapy regimen, FOLFIRINOX.
Sites will be added as they are approved
We recommend discussing treatment options directly with your oncologist. Amplia cannot provide medical advice nor discuss trial participation with you.
You can also find more information here clinicaltrials.gov
Follow Amplia Therapeutics for key clinical and commercial updates too https://ampliatx.com/